Add time:07/23/2019         Source:sciencedirect.com

2-epi-Jaspine B has been synthesized starting from (−)-diethyl tartrate in 12 simple steps and 26.6% overall yield. The key intermediate was obtained via stereoselective base-catalyzed intramolecular oxy-Michael conjugate addition followed by tandem hydrogenation/hydrogenolysis.

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