Add time:07/23/2019 Source:sciencedirect.com
The stereo- and enantioselective synthesis of the yellow scale pheromone, (S)-(-)-3,9-dimethyl 6-(1-methylethyl) (E)-5,8-decadien 1-ol acetate, from 3-(R)(̃+)-valerolactone 5 and [(4-methyl 3-pentenyl) sulfonyl] benzene 8 is described. The key step is the introduction of the isopropyl group by the stereoselective cross-coupling reaction of the dienesulfone 12 with isopropylmagnesium chloride in the presence of FeCl3.
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