Add time:07/23/2019         Source:sciencedirect.com

A number of azomustard derivatives have been shown by t.l.c. to consist of two components. In the case of CB 10-252, 4-[bis-(2-bromopropyl)amino]-2'-carboxy-2-methylazobenzene, these have been separated by preparative h.p.l.c. They are apparently diastereoisomers, chloroform solutions of which exhibit identical trans → cis photoisomerism and a thermal cis → trans reaction in the dark. They are also reduced identically by the soluble fraction of liver homogenate. The ability of a number of human tumour xenografts to reduce CB 10-252 was measured but the tumour with the most potent reductase activity was not inhibited by the drug in vivo.

We also recommend Trading Suppliers and Manufacturers of 2-(2-Bromopropyl)-1,3-dioxolane (cas 106334-26-3). Pls Click Website Link as below: cas 106334-26-3 suppliers