Add time:07/11/2019         Source:sciencedirect.com

Papain from Carica papaya demonstrated catalytic promiscuity was first discovered to catalyze the synthesis of trifluoromethyl carbinol derivatives via aldol reaction between α,α,α-trifluoromethyl ketones and aliphatic ketones in a mixed solvent of DMF and water. The best results of the corresponding aldol products with up to 99% yield and 30% ee were achieved.

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