Add time:07/26/2019 Source:sciencedirect.com
Racemic N-trifluoroacetyl pipecolic acid has been converted into (S)-N-Boc-pipecolic acid or (S)-N-Boc-2-piperidinemethanol by DCC/DMAP-induced diastereoselective esterification with (S)-α-methyl pantolactone, followed by a saponification or a reduction reaction and N-Boc protection.
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