Add time:07/26/2019         Source:sciencedirect.com

Platinum-based drugs, mainly cisplatin, are employed for the treatment of solid malignancies. However, cisplatin treatment often results in the development of chemoresistance, leading to therapeutic failure. Here, the antitumor activity of different trans-sulfonamide platinum complexes in a panel of human cell lines is presented. The cytotoxicity profiles and cell cycle analyses of these platinum sulfonamide complexes were different from those of cisplatin. These studies showed that complex 2b with cyclohexyldiamine and dansyl moieties had the best antitumoral activities.

We also recommend Trading Suppliers and Manufacturers of N-[3-(Dimethylamino)propyl]-4-methylbenzene-1-sulfonamide (cas 10256-77-6). Pls Click Website Link as below: cas 10256-77-6 suppliers