Add time:07/28/2019 Source:sciencedirect.com
Various N-(R)-(+)-(α-methylbenzyl)-(2R,3R)-disubstituted aziridines were prepared by intramolecular cyclization. The regioselective reduction of the ring C(3)-N bond in the presence of (Boc)2O by catalytic hydrogenation with atmospheric pressure of hydrogen provides (D)-phenylalaninol analogues in good yields.
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