Add time:07/13/2019 Source:sciencedirect.com
Optically active isatin-derived N,O-aminals were obtained through the catalytic asymmetric addition of various alcohols to isatin-derived N-Boc ketimines. Using 2′-phenyl cinchonidine thiourea as the catalyst, adducts were obtained in 96% yield and with up to 92% ee.
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