Reaction of 3-chloroallyltrimethylsilane with acid chloride and exploitation of a new regioselective synthesis of αβ-unsaturated epoxide-Science-Chemical Encyclopedia-lookchem

Reaction of 3-CHLOROALLYLTRIMETHYLSILANE (cas 18187-39-8) with acid chloride and exploitation of a new regioselective synthesis of αβ-unsaturated epoxide
Add time:07/29/2019 Source:sciencedirect.com

α-Chloro-βγ-unsaturated ketone (2) was synthesized from the reaction of 3-CHLOROALLYLTRIMETHYLSILANE (cas 18187-39-8) (1) with acid chloride. The ketone was converted into αβ-unsaturated epoxide (3) regioselectively in good yield via reduction with NaBH4 or LiAlH4 followed by treatment with NaOH. Treatment with methyl lithium instead of reduction gave homologous epoxide (5).

We also recommend Trading Suppliers and Manufacturers of 3-CHLOROALLYLTRIMETHYLSILANE (cas 18187-39-8). Pls Click Website Link as below: cas 18187-39-8 suppliers

Prev:Synthesis, structural characterization and properties of water-soluble N-(γ-propanoyl-amino acid)-chitosans
Next: Preparation and synthetic application of 3-bromoallyltrimethylsilane as hydroxypropenyl synthons)

Click to view details

Encyclopedia