Add time:07/11/2019         Source:sciencedirect.com

A new type of catalytic cascade pseudo four-component reaction has been found. The simple and facile pseudo four-component reaction of salicylaldehydes and cyclic or heterocyclic ketones with two molecules of malononitrile catalyzed by sodium acetate at ambient temperature results in the formation of 4-substituted 2-amino-4H-chromenes in 70–90% yields. Thus, a new simple and efficient ‘one-pot’ method to synthesize substituted 2-amino-4H-chromenes was found directly from such reasonable starting compounds as salicylaldehydes, cyclic or heterocyclic ketones and malononitrile.

We also recommend Trading Suppliers and Manufacturers of tetrahydro-2H-thiopyran-4-yl acetate (cas 40697-32-3). Pls Click Website Link as below: cas 40697-32-3 suppliers