Add time:08/04/2019         Source:sciencedirect.com

One new flavanonol, demethylmatteucinol (1), and nine new flavanone glucoside derivatives, matteflavosides H-J (2–4) and matteuinterates A-F (5–10), were isolated from the rhizomes of Matteuccia intermedia C.Chr., along with 21 known flavanones (11−31). Notably, all of them contain C-methylation in the A-ring. The structures of the compounds were elucidated by spectroscopic methods and chemical derivatization. The α-glycosidase inhibition assay indicated that compounds 12–17 showed potent inhibitory activity with IC50 values of 12.4–69.7 μM, which suggested their hypoglycemic effect.

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