Add time:08/02/2019 Source:sciencedirect.com
Superporous gastro-retentive Cefditoren (cas 104145-95-1) pivoxil tablets were prepared to improve the absorption and bioavailability of this drug and evaluated by varying the concentrations of carbopol and sodium carboxymethyl cellulose. The pre-compression and post-compression parameters were within acceptable pharmacopoeial limits. The swelling index indicates that formulations prepared with sodium carbonate have good porosity. The dissolution behaviour in vitro showed that the formulations that contained carbopol (100 mg) and sodium carboxymethyl cellulose (60 mg) had good controlled release (94.5%) by 24 h. Studies to evaluate the pharmacokinetics in vivo showed better bioavailability, area under the concentration–time curve, elimination rate constant and half-life than a commercially available conventional dosage form.
We also recommend Trading Suppliers and Manufacturers of Cefditoren (cas 104145-95-1). Pls Click Website Link as below: cas 104145-95-1 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View