Add time:08/02/2019         Source:sciencedirect.com

Development of enantioselective synthesis of precursor en route to paxilline indoloterpenoids is described. Evaluation of 25 diphosphine-based ligands has led to identification of JosiPhos derivative that allows for asymmetric conjugate addition of homoprenyl Grignard reagent to 2-methylcyclopent-2-en-1-one in excellent yield and with appreciable levels of enantioinduction. Application to the conjugate addition of other Grignard reagents is demonstrated.

We also recommend Trading Suppliers and Manufacturers of 2-butyl-5-methylcyclopent-2-en-1-one (cas 15263-86-2). Pls Click Website Link as below: cas 15263-86-2 suppliers