Add time:08/07/2019         Source:sciencedirect.com

Bis-(4-aminophenyl)-sulfone and several N,N'-diacyl derivatives have shown appreciable activity as antimalarials. With the assumption that a molecule more readily cleaved to a p-aminophenyl sulfur or oxidized sulfur anion, as a potential anti-PAB substance, might be a more effective antimalarial, a series of N,N',-diacyl derivatives of bis-(4-aminophenyl) disulfide was synthesized. Oxidation with peroxide followed by acylation gave the corresponding thiolsulfinates. Antimalarial activity was found for bis-(4-p-acetamidobenzenesulfonamidophenyl) disulfide and N,N′-bis-(α-aminoacyl) derivatives of bis-(4-aminophenyl)-sulfone.

We also recommend Trading Suppliers and Manufacturers of N,N-Bis(4-aminophenyl)-2,5-dimethoxy-1,4-benzenediamine (cas 106790-29-8). Pls Click Website Link as below: cas 106790-29-8 suppliers