Add time:08/07/2019 Source:sciencedirect.com
Dispersion of inorganic (magnesium chloride) nanoparticles in oil (octyl palmitate) was obtained by modifying a method based on solvent evaporation from nanometric droplets of water-in-oil nanoemulsion, which is usually used for obtaining organic nanoparticles. The particles size depends on the initial size of the emulsion droplets, and can be controlled by surfactant concentration and sonication time. At optimal conditions, the obtained nanoparticles are characterized by an average diameter of about 100 nm (dynamic light scattering and Cryo-TEM), by their amorphous structure when dispersed in oil, and according to thermal gravimetric analysis, by not contain free water after the evaporation process. The developed method is applicable for the preparation of various inorganic nanoparticles, and can be utilized for the formulation of new delivery systems based on inorganic nanoparticles of minerals/salts dispersed in oil.
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