Add time:08/07/2019 Source:sciencedirect.com
Asymmetric synthesis of 3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxides (DHBDs) was realized using readily available scandium(III)-inda-Pybox as the catalyst. It represents the first example focusing on systematic study of asymmetric synthesis of DHBDs, and a series of enantioselective 3-alkyl, or 3-aryl DHBDs were obtained with up to 93% ee.
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