An approach to an enantioselective synthesis of crisamicin A via a novel double Hauser–Kraus annulation strategy-Science-Chemical Encyclopedia-lookchem

An approach to an enantioselective synthesis of crisamicin A via a novel double Hauser–Kraus annulation strategy
Add time:08/05/2019 Source:sciencedirect.com

A double Hauser–Kraus annulation between biscyanophthalide 4 and the d-mannose derived enone 39 provides access to an advanced intermediate 54 that is an excellent scaffold to effect an enantioselective total synthesis of crisamicin A 1.

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