Add time:08/09/2019         Source:sciencedirect.com

We have developed an efficient one-pot method for the microwave-assisted synthesis of ureas and carbamates via a proposed Lossen rearrangement. Herein we report the first examples of the direct conversion of benzoyl chlorides into N,N′-disubstituted ureas and N-aryl carbamates using hydroxylamine-O-sulfonic acid as reagent. Using our general method, we have produced 11 examples of N,N′-disubstituted phenylureas in yields up to 95% using various substituted anilines, and primary and secondary amines. Additionally, we were able to generate a series of N-aryl carbamates in moderate yields using primary, secondary and tertiary alcohols.

We also recommend Trading Suppliers and Manufacturers of N-(m-methoxyphenyl)-N-methyl-p-toluenesulphonamide (cas 16437-31-3). Pls Click Website Link as below: cas 16437-31-3 suppliers