Add time:08/07/2019         Source:sciencedirect.com

A synthetic peptide corresponding to Cys-thymopoietin28–39 was synthesized and coupled by diazo linkages to aminophenyl thioether-derivatized paper disks. Disks were implanted the peritoneal cavities of mice, initially after soaking in complete Freund's adjuvant and subsequently, at 3 week intervals, without further treatment. After four implantations, 6/6 mice developed antibodies reacting with the synthetic peptide and with native thymopoietin. In contrast, mice conventionally immunized with peptide alone (six mice) or with peptide complexed with thyroglobulin (six mice) all failed to develop antibodies. Mice immunized with disks derivatized with Cys-thymopoietin9–20, corresponding to the other hydrophilic region of thymopoietin, also failed to develop antibodies. Thymopoietin28–39 corresponds to an antigenic hydrophilic region of thymopoietin that contains the pentapeptide active site (thymopoietin32–36, Arg-Lys-Asp-Val-Tyr).

We also recommend Trading Suppliers and Manufacturers of thymopoietin, Cys (28-39)- (cas 106939-01-9). Pls Click Website Link as below: cas 106939-01-9 suppliers