Add time:08/11/2019         Source:sciencedirect.com

A novel method of luminescence enhancement effect for the determination of Balofloxacin (cas 127294-70-6) (BLFX) was proposed. A new system of the BLFX–Eu3+–SDBS (sodium dodecylbenzene sulfonate) was investigated. It was found that SDBS significantly enhanced the luminescence intensity of the BLFX–Eu3+ complex (about 20-fold). Under the optimized experimental conditions, the system exhibits an excellent linear relationship between the enhanced luminescence intensity and the concentration of BLFX over the range of 1.0×10−8–8.0×10−7 mol L−1 with a correlation coefficient (R) of 0.9994, and the detection limit (3σ) of the method was determined as 2.0×10−9 mol L−1. This method has been successfully applied for the determination of BLFX in pharmaceuticals and human urine/serum samples. Compared with most of the other methods reported, the rapid and simple procedure proposed in the text offers higher sensitivity, wider linear range, and better stability.

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