Add time:07/16/2019         Source:sciencedirect.com

A facile method has been developed for the preparation of densely functionalized tricyclic fused pyrimidine derivatives by three-component [3+2+1] cyclization. Fairly good yields of the products (up to 88%), the ready availability of the low-cost starting materials, the catalyst-free and mild conditions are the main advantages of this method.

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