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  • Microwave-assisted synthesis and antioxidant activity of palmitoyl-epigallocatechin gallate
  • Add time:08/14/2019         Source:sciencedirect.com

    Palmitoyl-epigallocatechin gallate (p-EGCG), a palmitic acid ester derivative of epigallocatechin gallate (EGCG), has been declared with high bioactivity. Synthesis of p-EGCG with microwave irradiation as well as its antioxidant activity by Rancimat test was investigated in this study. With microwave assistance, higher conversion rate (85.12%) was observed in a shorter reaction time (2 h) than that of conventional method. The major product was identified as p-EGCG with a purity of 91.73% after separation by Medium Pressure Liquid Chromatography. Accelerated oxidation revealed that p-EGCG exerted stronger antioxidant activity than EGCG in the control of soybean oil oxidation. With an addition of 200 mg/kg p-EGCG, the shelf-life of soybean oil at 25 °C was predicted to be 16.61 months. The results suggested that p-EGCG may serve as a potential antioxidant and contribute to the preservation of edible oil or fat-based food.

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