Add time:08/09/2019 Source:sciencedirect.com
A base labile urethane (Bnpeoc) group derived from 2,2-bis(4′-nitrophenyl)ethan-1-ol has been developed as an amine protecting group. This protecting group may be cleaved using the reagents DBN, DBU, DBU/HOAc and piperidine. The preparations of Nα-Bnpeoc amino acids and applications to peptide/glycopeptide synthesis are described.
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