Add time:08/17/2019 Source:sciencedirect.com
A novel THIAZOLE ORANGE (cas 107091-89-4) (TO) derivative 3 has been synthesized and it could give the fluorescence turn-on responsive signal upon binding to nucleotides and besides, it exhibits high selectivity toward adenosine triphosphate (ATP) over other tested nucleotides. The nonlinear sigmoidal-responded pattern of the fluorescent spectra of 3 upon binding to ATP indicates that the positive cooperative interactions amplify the selective information. A possible co-assembled process of 3/ATP is postulated based on the UV–vis, fluorescent, 1H NMR and DLS titrations.
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