In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter-Science-Chemical Encyclopedia-lookchem

In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter
Add time:08/11/2019 Source:sciencedirect.com

IntroductionP-glycoprotein (P-gp) is an energy-dependent transporter that contributes to the efflux of a wide range of xenobiotics at the blood–brain barrier playing a role in drug-resistance or therapy failure. In this study, we evaluated [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine ([123I]-FMIP) as a novel single photon emission computed tomography (SPECT) tracer for imaging P-gp at the brain in vivo.

We also recommend Trading Suppliers and Manufacturers of 4-Iodobenzyl alcohol (cas 18282-51-4). Pls Click Website Link as below: cas 18282-51-4 suppliers

Prev:Conformational features of meso-tetrathienylporphyrins and photosensitising properties of their β-1-acetyl-2-oxopropyl derivatives
Next: Original paperSubstituted spiro[chroman-4,5′-thiazolidine]-2′,4′-diones as aldose reductase inhibitorsSpiro[chromanne-4,5′-thiazolidine]diones-2′,4′ substituées inhibiteurs de l'aldose réductase)

Click to view details

Encyclopedia