Add time:08/13/2019         Source:sciencedirect.com

Alkylation and aldol reactions carried out on axially chiral, diastereoenriched oxazolidinedione derivatives were found to be highly stereoselective with respect to substitution at the 5-position of the oxazolidindione ring. Thus, diastereoenriched 5-methyl-3-(o-iodophenyl)-2-thioxo-4-oxazolidinone and 5-methyl-3-(o-aryl)-2,4-oxazolidinediones were prepared and lithiated at C-5 of the oxazolidine ring and the subsequent electrophilic quench with alkyl halides or benzaldehyde yielded products with the same diastereomer ratios as the starting materials.

We also recommend Trading Suppliers and Manufacturers of 3-ETHYL-2-THIOXO-4-OXAZOLIDINONE (cas 10574-66-0). Pls Click Website Link as below: cas 10574-66-0 suppliers