Add time:07/13/2019         Source:sciencedirect.com

A convenient and user-friendly method to yield benzamides from primary and secondary amines and various benzylic alcohols in the presence of a cheap iron salt (FeCl2·4H2O) and tert-butylhydroperoxide (70% in water) as a stoichiometric oxidant is described. Control experiments indicated that this reaction might involve radical species. This method proved to be general, generating a family of 30 benzamides and was applied to the preparative synthesis of anti-anxiety drug moclobemide.

We also recommend Trading Suppliers and Manufacturers of 4-ethyl-N-(4-methylbenzyl)benzamide (cas 746632-76-8). Pls Click Website Link as below: cas 746632-76-8 suppliers