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  • Toxic effects of new ethyl-carbamates on the morphology, mortality and acetylcholinesterase activity of Eisenia foetida
  • Add time:08/14/2019         Source:sciencedirect.com

    The toxicity of the ixodicidal carbamates ethyl-4-bromophenyl carbamate (LQM 919), ethyl-4-chlorophenyl carbamate (LQM 996) and propoxur on Eisenia foetida adults was evaluated to estimate their ecotoxic potential. The earthworm mortality and weight loss produced by the three evaluated carbamates showed a concentration-dependent effect (p < 0.0001) in the contact filter paper test (CFPT). In the artificial soil test (AST), mortality increased in relation to the exposure time (p < 0.0001) and the concentration (p < 0.01) of the carbamates. Only the earthworms exposed in the CFPT showed morphological alterations. According to the LC50 obtained in the CFPT, the three carbamates were classified as very toxic and, according to the LC50 obtained in the AST, the three carbamates were classified as highly toxic for E. foetida. The values of ki and kd indicated that LQM 919 and LQM 996 are weak inhibitors with lower affinity for the acetylcholinesterase of E. foetida than that of propoxur. The concentrations in the CFPT and AST at which 100% mortality was observed in E. foetida were 64- and 4-fold higher, respectively, than the egg hatching inhibitory concentration 99% reported for ticks.

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