Add time:08/13/2019         Source:sciencedirect.com

A novel and simple one-step method for the aluminum catalyzed self-aldol reaction of valeraldehyde is presented. This mechanochemical method utilizes high-energy ball milling to produce fresh aluminum surface in the presence of valeraldehyde as a liquid milling solution. The fresh surface created through the mechanical attrition of aluminum particles during milling is highly reactive, and serves to catalyze the self-aldol reaction of valeraldehyde to form 2-propyl-3-hydroxyl-heptanal.

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