New strategy for racemization of 2-amino-1,3-propanediols, key intermediates for the synthesis of antibiotic drugs-Science-Chemical Encyclopedia-lookchem

New strategy for racemization of 2-amino-1,3-propanediols, key intermediates for the synthesis of antibiotic drugs
Add time:08/16/2019 Source:sciencedirect.com

A new strategy for racemization of the 2-amino-1,3-propanediol 2b, based on a chemoselective oxazoline ring formation and a highly diastereoselective reduction of the ketone 4 is reported.

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