Add time:08/15/2019         Source:sciencedirect.com

The synthesis of (1R,2S)- and (1S,2R)-1-amino-2-(hydroxymethyl)cyclopropanephosphonic acids was accomplished using different strategies. The (1R,2S)-stereoisomer could be efficiently obtained by the cyclopropanation of ethyl diethoxyphosphorylacetate with the cyclic sulfate derived from (S)-3-benzyloxy-1,2-propandiol as a key step. The (1S,2R)-stereoisomer was synthesized from a readily available (1S,5R)-3-oxabicyclo[3.1.0]hexan-2-on-1-phosphonate.

We also recommend Trading Suppliers and Manufacturers of Cyclopropanecarboxylic acid, 1-aMino-, butyl ester (cas 104544-08-3). Pls Click Website Link as below: cas 104544-08-3 suppliers