Add time:08/14/2019         Source:sciencedirect.com

Quingestanol (cas 10592-65-1) acetate is a potent progestogen which significantly alters the histology and histochemistry of the endometrium when studied by light and electron microscopy. The steroid did not alter transport mechanisms across the cell surfaces but, probably because of competition with estrogen for binding sites, altered sequences in carbohydrate and protein synthesis. It caused the development of platelet aggregates within the endometrial vessels and degeneration of endometrial cells through the entire menstrual cycle. The effectiveness of quingestanol acetate as a “mini-pill” is related to its alteration of the biology of the endometrial cells as well as its suppression of FSH and LH.

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