Asymmetric Syntheses of (2S,3S,6S)-, (2S,3S,6R)-, and (2R,3R,6S)-2,3-Methano-2,6-diaminopimelic Acids. Studies Directed to the Design of Novel Substrate-based Inhibitors of L,L-Diaminopimelate Epimerase-Science-Chemical Encyclopedia-lookchem

Asymmetric Syntheses of (2S,3S,6S)-, (2S,3S,6R)-, and (2R,3R,6S)-2,3-Methano-2,6-diaminopimelic Acids. Studies Directed to the Design of Novel Substrate-based Inhibitors of L,L-Diaminopimelate Epimerase
Add time:07/13/2019 Source:sciencedirect.com

The asymmetric syntheses ot (2S,3S,6S)-, (2S,3S,6R)-, and (2R,3R,6S)-2,3-methano-2,6-diaminopimelic acids (7a-c) is described. The synthesis features phosphonate coupling of 13 and 14 to form the corresponding E-olefins which are subsequently cyclopropanated and deprotected under dissolving metal conditions.

We also recommend Trading Suppliers and Manufacturers of (2S,6S)-6-ethyl-3,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol hydrochloride (1:1) (cas 56711-09-2). Pls Click Website Link as below: cas 56711-09-2 suppliers

Prev:Development of amino- and dimethylcarbamate-substituted resorcinol as programmed cell death-1 (PD-1) inhibitor
Next: Growth, characterization, NLO and biological activities of Fe(III) ions doped Mn(II) L-Histidine hydrochloride monohydrate crystals)

Click to view details

Encyclopedia