Add time:08/15/2019 Source:sciencedirect.com
SummaryIt has been demonstrated in a rabbit reticulocyte system that phenomycin selectively blocks the initiation of globin synthesis. The N-terminal incorporation of valine or methionine is more markedly inhibited by the antibiotic than the total incorporation. The 80S initiation complex is accumulated in the presence of phenomycin. The initial dipeptide formation (Met-Val) is significantly affected by the antibiotic.
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