Enzymatic resolution of ethyl 3-hydroxy-2(1′substituted-methylidene)-butyrate by Pseudomonas cepacia lipase catalyzed acetylation-Science-Chemical Encyclopedia-lookchem

Enzymatic resolution of ethyl 3-hydroxy-2(1′substituted-methylidene)-butyrate by Pseudomonas cepacia lipase catalyzed acetylation
Add time:07/14/2019 Source:sciencedirect.com

Enzymatic resolution of a series of enantiomerically pure ethyl 3-hydroxy-2(1′substituted-methylidene)-butyrates was performed using Pseudomonas cepacia lipase (EC 3.1.1.3) as a catalyst. Optically active ethyl 3-hydroxy-2(1′substituted-methylidene)-butyrates, as well as their acetates, were obtained from this reaction in good yield and excellent enantiomeric excess.

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