Add time:08/16/2019         Source:sciencedirect.com

Five new di-Schiff base nickel(II) complexes (1–5) of salen type ligands were synthesized in-situ by condensation of 3-(dimethylamino)-1-propylamine with 2-hydroxybenzaldehyde, 2-hydroxy-5-methyl benzaldehyde, 2-hydroxy-5-bromo benzaldehyde, 2-hydroxy-5-nitrobenzaldehyde and 2-hydroxy-1-naphthaldehyde to obtain L1–L5, respectively and complexed with nickel chloride. Single crystal X-ray diffraction studies of complexes 1 and 5 showed a distorted octahedral and distorted square-planar geometry, respectively around nickel atoms. The cyclic voltammetry of complexes 1–5 showed redox peaks near cathodic and anodic regions assignable to the Ni2+/Ni+ and Ni2+/Ni3+ redox couples, respectively. The binding studies of complexes with calf thymus DNA (ctDNA) showed an intercalation mode of binding. The nuclease activity of the complexes with pBR322 plasmid DNA showed efficient oxidative cleavage by the formation of singlet oxygen species in presence of H2O2. All nickel(II) complexes were found to have greater zone inhibition diameter when analyzed for antimicrobial property against four bacterial species and two human pathogenic fungal species.

We also recommend Trading Suppliers and Manufacturers of 3-Methyl-5-nitrobenzaldehyde (cas 107757-06-2). Pls Click Website Link as below: cas 107757-06-2 suppliers