Add time:08/16/2019         Source:sciencedirect.com

A novel method derived from Kaden's modification1 of the Richman and Atkins's cyclization2 using tosylated synthons allows the unequivocal synthesis of 1 and 8-monofunctionalized 1,4,8,12-tetraazacyclo-pentadecane. Both syntheses are described.

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