Add time:08/17/2019         Source:sciencedirect.com

A novel peptide, H-Gly-Phe-Trp-Asn-Lys-OH, was isolated from eel guts. This peptide, termed eel intestinal pentapeptide (EIPP), enhanced the frequency of the spontaneous contractions and increased the basal tone of the circular muscle of the esophagogastric junction. Furthermore, EIPP enhanced the spontaneous contractions of the longitudinal muscle strips of the gut and stomach, and of the circular muscle of the gastro-intestinal junction. The peptide may be a physiological regulatory peptide in the gastro-intestinal tract of the eel.

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