Add time:08/20/2019         Source:sciencedirect.com

Amino acid sequence analysis of a protein from chicken thymus tissue which promotes immunological maturity in chicken bone marrow cells in culture has established sequences of a 45-residue fragment, a 24-residue fragment and a 9-residue and an 8-residue peptide. Independent comparison of the 45- and 24-residue fragments with known amino acid sequences by computer search has unequivocally identified avian thymic hormone (cas 135750-90-2) as a parvalbumin. This is the first demonstration that a protein previously identified by a biological function is a parvalbumin.

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