Add time:08/19/2019         Source:sciencedirect.com

In connection with the chemical-medicinal work 5-chloro-2-(3-chloro-2-hydroxypropoxy)-benzhydrylamine was prepared by a three-step synthesis. Compound I was reacted with epichlorohydrin and the formed 3-(2-benzyl 4-chlorophenoxy)-2-hydroxypropylchloride (II) was then converted to III by free-radical bromination, which was not isolated, but converted to compound V by amination.

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