Resolution of 1-phenoxy-, 1-phenylmethoxy- and 1-(2-phenylethoxy)-2-propanol and their butanoates by hydrolysis with lipase B from Candida antarctica-Science-Chemical Encyclopedia-lookchem

Resolution of 1-phenoxy-, 1-phenylmethoxy- and 1-(2-phenylethoxy)-2-propanol and their butanoates by hydrolysis with lipase B from Candida antarctica
Add time:07/14/2019 Source:sciencedirect.com

Resolutions of butanoic esters of 1-phenoxy-2-propanol, 1-phenylmethoxy-2-propanol and 1-(2-phenylethoxy)-2-propanol have been studied with four different lipases as catalysts. Using lipase B from Candida antarctica very high enantiomer ratios were obtained. These substrate-lipase pairs represent an excellent way of getting enantiomerically pure protected 1,2-propanediols in high chemical yield.

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