Encyclopedia

  • Research ArticlesInteraction of Amphotericin B With Cholesteryl Palmityl Carbonate Ester
  • Add time:08/19/2019         Source:sciencedirect.com

    ABSTRACTA cholesteryl carbonate ester was prepared and evaluated as a possible thermotropic liquid crystal excipient for dry powder inhalers. Cholesteryl palmityl carbonate (CPC) was synthesized, and the phase behavior was characterized by differential scanning calorimetry, transmission electron microscopy, polarized light microscope, small angle X-ray diffraction, and solid-state nuclear magnetic resonance spectroscopy. Amphotericin B (AmB) was incorporated into CPC at various mole% (7.7, 14.3, 25, 33.3, and 50) using a solvent evaporation method. The amount of AmB loaded into liquid crystal was limited. The mixture of AmB in liquid crystal did not produce a new complex; rather, the addition of AmB affected the orientational order and the motional aspects of liquid crystal molecules. © 2010 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 99:4593–4602, 2010

    We also recommend Trading Suppliers and Manufacturers of CHOLESTEROL N-NONYL CARBONATE (cas 15455-83-1). Pls Click Website Link as below: cas 15455-83-1 suppliers


    Prev:Interaction of polyhedral oligomeric silsesquioxane containing epoxycyclohexyl groups with cholesterol at the air/water interface
    Next: Enhanced capacities and selectivities for cholesterol in aqueous media by molecular imprinting: role of novel cross-linkers)

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View