Add time:07/22/2019 Source:sciencedirect.com
A mild and efficient copper-mediated trifluoromethylthiolation of acid chlorides using (bpy)CuSCF3 has been developed. A wide range of S-trifluoromethyl esters were synthesized in good to excellent yields and various functional groups, including cyano, ether, ester, halide, nitro, et al. were well tolerated.
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