Add time:08/25/2019         Source:sciencedirect.com

N,N-Dimethylcarbamoyl(trimethyl)silane reacted with N-Boc-imines in anhydrous benzene under catalysts-free conditions to afford N-Boc-protected α-amino amides in good yields (72–89%). The electronic property and the steric hindrance of substituent on the N-Boc-imines affected the reaction.

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