Add time:08/27/2019         Source:sciencedirect.com

Inhalable nitrites consist primarily of the volatile alkyl nitrites, amyl nitrite (Chemical s Service Registry Number (CAS) 463-04-07), butyl nitrite (CAS 544-16-1), and isobutyl nitrite (CAS 542-56-3). While amyl nitrite has been used clinically in humans since the late 1800s; other members of this class are found only in nonpharmaceutical preparations. Nitrite inhalants have become well recognized as substances of abuse. Exposure may affect the cardiovascular, hematopoietic, pulmonary, and central nervous systems. Treatment consists of intravenous methylene blue for methemoglobinemia and supportive measures for other symptoms.

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