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  • Conformations of peptides containing Z-α,β-dehydroleucine (cas 113586-23-5) (ΔZLeu). A comparison of Boc-Pro-ΔZLeu-Gly-NHEt and Boc-Pro-ΔZPhe-Gly-NHEt
  • Add time:08/20/2019         Source:sciencedirect.com

    Two tripeptides of the type Boc-Pro-ΔZX-Gly-NHEt (where X = Leu, Phe) have been synthesized and their solution conformations investigated by 270 MHz 1H n.m.r. and i.r. spectroscopy. These conformational studies indicated that ΔZLeu, similar to ΔZPhe, has a strong tendency to stabilize folded Type II β-turn conformations when present at i + 2 position.

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