Add time:08/22/2019         Source:sciencedirect.com

A metal-free route involving a sequential reaction of 2-alknylbenzoate and aryl-1,2-diamine is described for the generation of 2-(quinoxalin-2-yl)benzoate. The sequential reaction combines NBS-mediated diketonization of 2-alknylbenzoate and condensation reaction with aryl-1,2-diamine, and proceeds smoothly under mild reaction conditions and an array of 2-(quinoxalin-2-yl)benzoate is achieved with high efficiency and excellent functional group tolerance. Mechanism studies indicate oxygen transfer reaction is observed and water is incorporated into neighboring ester group.

We also recommend Trading Suppliers and Manufacturers of 2-diaMine (cas 113638-49-6). Pls Click Website Link as below: cas 113638-49-6 suppliers