Add time:08/25/2019         Source:sciencedirect.com

The reaction of aromatic 1,2-diamines with trichloromethylcarbinols under mild, basic phase-transfer conditions provided expedient access to 3,3-disubsituted quinoxalin-2(1H)-ones in good to moderate yields. The use of unsymmetrical aryl diamines gave a regioisomeric mixture of products with the ratio shown to be dependent on the electronic nature of the aromatic substituents. 2,3-Diaminopyridines could also be used, showing excellent selectivity for the dihydro[3,2-b]pyridopyrazin-2-one isomer.

We also recommend Trading Suppliers and Manufacturers of 2-diaMine (cas 113638-49-6). Pls Click Website Link as below: cas 113638-49-6 suppliers