Add time:08/22/2019         Source:sciencedirect.com

BackgroundSustained, low- and mid-level (3–6%), radial stretching combined with varying concentrations of Sodium pyruvate (cas 113-24-6) (NaPy) supplement increase the migration rate during microscale gap closure following an in vitro injury; NaPy is a physiological supplement often used in cell-culture media. Recently we showed that low-level tensile strains accelerate in vitro kinematics during en masse cell migration; topically applied mechanical deformations also accelerate in vivo healing in larger wounds. The constituents and nutrients at injury sites change. Thus, we combine a supplement with stretching conditions to effectively accelerate wound healing.

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