Synthesis of 5-amino-2-aminoalkyl-1,3-oxazol-4-ylphosphonic acid derivatives and their use in the preparation of phosphorylated peptidomimetics-Science-Chemical Encyclopedia-lookchem

Synthesis of 5-amino-2-aminoalkyl-1,3-oxazol-4-ylphosphonic acid derivatives and their use in the preparation of phosphorylated peptidomimetics
Add time:08/21/2019 Source:sciencedirect.com

Starting from phthalimidoalkanoylamines 1 (amino-protected derivatives of glycine, β-alanine, γ-amino butyric, δ-amino valeric, and ε-amino caproic acids), a facile synthetic method has been developed to obtain diethyl 5-alkyl(dialkyl)amino-2-aminoalkyl-1,3-oxazol-4-ylphosphonates 7, which have been further used in the preparation of phosphorylated peptidomimetics 10 and 12.

We also recommend Trading Suppliers and Manufacturers of 2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-METHYLPENTANOIC ACID (cas 19506-84-4). Pls Click Website Link as below: cas 19506-84-4 suppliers

Prev:Data articleSynthesis, crystal structure and Hirshfeld surface analysis of a benzoxazole derivative [2-[2-(4-Methylphenyl)ethenyl]-1,3-benzoxazole]
Next: Short CommunicationSynthesis of enantiomerically pure 4-polyfluoromethyl-4-hydroxy-homoprolines by intramolecular cyclization of 6-amino-5-polyfluoromethyl-hex-2-enoic acids)

Click to view details

Encyclopedia